seasonal coronavirus – Communicable Diseases Research

Human seasonal coronavirus neutralization and COVID-19 severity

인간 계절 코로나 바이러스 중화 및 COVID-19 심각성

Article

Published on 2022-10-012022-09-12
Journal: Journal of medical virology
[Category] COVID19(2023년), MERS, SARS, 진단,

Pre-existing anti-HCoV-OC43 immunity influences the durability and cross-reactivity of humoral response to SARS-CoV-2 vaccination

Article

Published on 2022-09-022022-11-15
Journal: Frontiers in Cellular and Infection Microbiology
[Category] SARS, 진단, 치료기술,

[키워드] Analysis anti-HCoV-OC43 anti-nucleoprotein anti-RBD antibodies antibody binding chemiluminescence immunoassay conducted coronavirus coronavirus vaccine correlation cross-protection cross-reactivity demonstrated detect ELISA enzyme-linked immunosorbent HCoV-229E HCoV-HKU1 HCoV-NL63 HCoV-OC43 humoral Humoral response IgG Immunity Immunoglobulin inactivated individuals influence neutralization Neutralization antibody neutralizing antibody Outbreaks performed positively correlated Protective protective immunity Protein pseudovirus S1 IgG S1 subunit SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine seasonal coronavirus seasonal human coronavirus. second vaccination statistically significant vaccination Vaccine vaccinee vaccinees viral neutralization
[DOI] 10.3389/fcimb.2022.978440 PMC 바로가기

Clinical significance and role of coinfections with respiratory pathogens among individuals with confirmed severe acute respiratory syndrome coronavirus-2 infection

Article

Published on 2022-09-022022-11-15
Journal: Frontiers in Public Health
[Category] SARS, 치료기술,

[키워드] 229E acute respiratory syndrome Adenovirus AdV age analyzed average C-reactive protein (CRP cause children Clinical data clinical feature clinical picture Clinical significance Coinfection collected Combination complications Coronavirus-2 COVID-19 CRP detect determine Diseases distribution highest HKU1 Hospital stay hospitalized patient individual Infection Influenza influenza A Influenza virus involved lymphocyte métapneumovirus NL63 OC43 other respiratory virus outcome Outpatient parainfluenza virus Patient patients with SARS Prevalence Prevent proportion respiratory pathogen respiratory syncytial virus respiratory virus respiratory viruses rhinovirus RSV SARS CoV-2 SARS-CoV-2 SARS-CoV-2 positive patient Screening seasonal coronavirus specimen tested the disease the mean Treatment Viral load Viral load. virus was determined was used worsening
[DOI] 10.3389/fpubh.2022.959319 PMC 바로가기

Decreased Passive Immunity to Respiratory Viruses through Human Milk during the COVID-19 Pandemic

Article

Published on 2022-08-312022-11-15
Journal: Microbiology Spectrum
[Category] 진단,

[키워드] antibodies antibody association binding breast milk circulation consequence Coronaviruses coronaviruses. COVID-19 COVID-19 pandemic decrease Decreased develop explain HCoV-HKU1 HCoV-NL63 HCoV-OC43 help Hospital admission Hospitalization Human human milk Humoral immunity hygiene IgA IgG IgG level immune system Immunity Infant Infants Infection infections Influenza lifted lockdown Luminex assay measure milk mother pandemic Passive passive immunity predict Prevent preventative measure preventative measures provide reduced respiratory respiratory infections respiratory syncytial virus respiratory virus resulting RSV seasonal coronavirus serum subsequent viral respiratory virus viruses was reduced
[DOI] 10.1128/spectrum.00405-22 PMC 바로가기

Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination Boosts Neutralizing Activity Against Seasonal Human Coronaviruses

중증 급성 호흡기 증후군 코로나바이러스 2 백신 접종은 계절성 인간 코로나바이러스에 대한 중화 활성을 향상시킵니다

Article

Published on 2022-08-242022-09-11
Journal: Clinical Infectious Diseases: An Official Publicat
[Category] SARS, 치료법,

[키워드] 229E activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Against analyzed average BNT162b2 causative agent ChAdOx1 ChAdOx1 nCoV-19 circulating colds common cold Concentration coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccination COVID-19 vaccinations cross-neutralization cross-protection determined by Efficiency Endemic Gene Expression HCoV HCoV-229E HCoV-NL63 HCoV-OC43 HCoVs Heterologous Huh-7 cells Human human coronavirus incubated individual inhibitory activity MERS MERS-CoV Middle East Middle East respiratory syndrome MOST neutralization neutralize Neutralizing activity NL63 nucleocapsid expression OC43 Preexisting immunity pseudoparticle pseudovirion pseudovirions reporter reporter gene respiratory SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 vaccination seasonal seasonal coronavirus seasonal coronaviruses seasonal coronaviruses. sera severe acute respiratory syndrome Coronavirus significantly increased Spike proteins these viruses vaccination Viral RNA virus
[DOI] 10.1093/cid/ciac057 PMC 바로가기 [Article Type] Article

Longitudinal Assessment of SARS-CoV-2-Specific T Cell Cytokine-Producing Responses for 1 Year Reveals Persistence of Multicytokine Proliferative Responses, with Greater Immunity Associated with Disease Severity

1년 동안 SARS-CoV-2-특이적 T 세포 사이토카인 생성 반응에 대한 종단 평가는 질병 중증도와 관련된 더 큰 면역과 함께 다중 사이토카인 증식 반응의 지속성을 보여줍니다

Article

Published on 2022-07-132022-09-11
Journal: Journal of Virology
[Category] COVID19(2023년), SARS, 치료법,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 all subjects assessment average CD4 CD8 Cell Cell-mediated immunity clone coronavirus Coronaviruses Critical cytokine cytokine response Cytokines declined demonstrated dominant ELISPOT ELISpot assay envelope enzyme-linked immunosorbent epitope Epitopes Ex vivo female Frequency gamma interferon granzyme B greater GzmB highlight IFN-γ IL-2 immune immune modeling. Immunity immunodominant immunodominant epitope immunodominant epitopes induce Infection interferon interleukin interleukin 2 kill longitudinal male median membrane nucleocapsid observation other coronaviruses peaked persistence post-symptom onset potent predicted produced producing proliferative PSO reduced regions response robust SARS-CoV-1 SARS-CoV-2 seasonal coronavirus seasonal coronaviruses severe acute respiratory syndrome Coronavirus severe disease structural protein structural proteins subject survivor T cell T cell immunity T cell memory T cell response T cell responses T cells target cells Vaccine viral infections Year
[DOI] 10.1128/jvi.00509-22 PMC 바로가기 [Article Type] Article

Recapitulating infection, thermal sensitivity and antiviral treatment of seasonal coronaviruses in human airway organoids

인간 기도 오르가노이드에서 계절성 코로나바이러스의 감염, 열 민감도 및 항바이러스 치료 요약

Article

Published on 2022-07-012022-09-11
Journal: EBioMedicine
[Category] 치료제,

[키워드] 229E Airway organoids Analysis analysis antiviral activity antiviral therapy Antiviral treatment approved conditions Coronavirus infection Coronavirus infections COVID COVID19 development experimental model facilitate favor funding help host response Human human airway Infection infections Infectious virus inhibited interactions Kinetics medication medications Mild molnupiravir Netherland NL63 OC43 occur organization Organoid Pathogenesis phenotype populations Remdesivir replicate Replication Research research and development resulting RNA sequencing robust seasonal seasonal coronavirus seasonal coronaviruses severe complication severe complications Society Support supported temperature tested therapeutic thermal Thermal sensitivity Transcriptome transcriptomic Transmissibility upper respiratory tract viral replication virus replication Virus-host interaction Virus-host interactions virus-host interactions. was performed was tested
[DOI] 10.1016/j.ebiom.2022.104132 PMC 바로가기 [Article Type] Article

Serological Follow-Up Study Indicates High Seasonal Coronavirus Infection and Reinfection Rates in Early Childhood

혈청학적 후속 연구는 유아기에 높은 계절성 코로나바이러스 감염 및 재감염율을 나타냅니다

Article

Published on 2022-06-292022-09-12
Journal: Microbiology Spectrum
[Category] MERS, 진단,

[키워드] 229E age analyzed antibodies antibody antibody level Antibody Response caused changes in Characteristics childhood children collected coronavirus Coronavirus infection correlation cross-reactivity declined elicited enzyme enzyme immunoassay Follow-up follow-up study groups HKU1 human coronavirus humoral immune response IgG antibody immunoassay Increased indicated Infection information knowledge NL63 observation OC43 Primary infection Rate Reinfection respiratory infection respiratory infections seasonal seasonal coronavirus seasonal coronavirus serological serology Serology. seropositive serum specific antibody specimen spread of COVID-19 suggested the antibody virus were measured
[DOI] 10.1128/spectrum.01967-21 PMC 바로가기 [Article Type] Article

Structural mapping of antibody landscapes to human betacoronavirus spike proteins

인간 베타 코로나바이러스 스파이크 단백질에 대한 항체 지형의 구조적 매핑

Article

Published on 2022-05-062022-09-12
Journal: Science Advances
[Category] COVID19(2023년), MERS, SARS, 진단,

SARS-CoV-2 mRNA vaccine induces robust specific and cross-reactive IgG and unequal neutralizing antibodies in naive and previously infected people

SARS-CoV-2 mRNA 백신은 순진하고 이전에 감염된 사람들에게 강력한 특이적이고 교차 반응성인 IgG 및 불평등한 중화 항체를 유도합니다.

Article

Published on 2022-02-012022-09-11
Journal: Cell Reports
[Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Alpha alpha and delta variants antibody Antibody Response Complete coronavirus disease Coronavirus disease 2019 Coronavirus-2 correlates of protection COVID-19 Critical cross-reactive cross-reactive antibodies cross-reactive antibody delta variant Endemic first dose Frequency healthy individual human endemic coronavirus IgG individual individuals induce infected individual infected individuals Infection mRNA mRNA vaccine naïve individuals neutralization Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing antibody response neutralizing antibody responses pandemic reference strain respiratory robust SARS-CoV-2 SARS-CoV-2 neutralizing antibodies SARS-CoV-2 neutralizing antibody SARS-CoV-2 spike SARS-CoV-2 variant SARS-CoV-2 variants seasonal coronavirus seasonal coronaviruses second dose serostatus serostatus determination Seven Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 strength Support understanding vaccination Vaccination strategy vaccine dose Variability variability in antibody response. variants
[DOI] 10.1016/j.celrep.2022.110336 PMC 바로가기 [Article Type] Article